Hypoglycaemic event occurred in the advanced hybrid closed-loop system group, determined
Hybrid closed-loop system (mean difference −0♰6% p<0♰001 for non-inferiority). Of time with glucose levels below 54 mg/dL (<3♰ mmol/L) was 0♴6% (SD 0♴2) at baseline,Ġ♵0% (0♳5) during use of the 670G system, and 0♴6% (0♳3) during use of the advanced Of time with daytime glucose levels above 180 mg/dL (>10♰ mmol/L) was 42% (SD 13)Īt baseline, 37% (9) during use of the 670G system, and 34% (9) during use of theĪdvanced hybrid closed-loop system (mean difference [advanced hybrid closed-loop system MeanĪge was 19 years (SD 4) and 70 (62%) of 113 participants were female. Findingsīetween June 3 and Aug 22, 2019, 113 individuals were enrolled into the trial. This trial is registered with, NCT03040414, and is now complete.
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(<3♰ mmol/L) calculated over a full 24-h period, tested for non-inferiority (non-inferiority Tested for superiority, and proportion of time that glucose levels were below 54 mg/dL Glucose levels were above 180 mg/dL (>10♰ mmol/L) during 0600 h to 2359 h (ie, daytime), Outcomes, measured with continuous glucose monitoring, were proportion of time that Masking was not possible due to the nature of the systems used. Were crossed over with no washout period, to the other group for use for another 12 Hybrid closed-loop system (Medtronic) for the first 12-week period, and then participants Of a MiniMed 670G hybrid closed-loop system (670G) or the investigational advanced HbA 1c and use of a personal MiniMed 670G system (Medtronic) at enrolment, to either use With a permuted block design (block sizes of two and four), stratified by baseline The interrelationship between human leukocyte antigen immunogenetics and environmental factors and their contribution to the emergence of type 1 diabetes (T1D) were studied in Jewish immigrants from Ethiopia in Israel. Monitor, participants were randomly assigned (1:1) using a computer-generated sequence,
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Run-in period to teach participants how to use the study pump and continuous glucose Practices, four in the USA, and one each in Germany, Israel, and Slovenia.
Multiple daily insulin injections, and glycated haemoglobin (HbA 1c) levels of 7♰–11♰% (53–97 mmol/mol) were recruited from seven academic-based endocrinology Type 1 diabetes with a duration of at least 1 year, using either an insulin pump or Preventing the risk of DKA at diagnosis is one of the major goals of the Australian Type 1 Diabetes National Screening Program pilot which will start recruiting in April 2022. Regulation ), individuals aged 14–29 years old, with a clinical diagnosis of In this multinational, randomised, crossover trial (Fuzzy Logic Automated Insulin The Lancet Regional Health – Western Pacific.The Lancet Regional Health – Southeast Asia.The Lancet Gastroenterology & Hepatology.
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